Table 1.
Bioactivity of paclitaxel and analogs
| Compound | Tubulin Assembly activity, ED50, μM | A2780 Cytotoxicity IC50, μM |
|---|---|---|
| 1 (PTX) | 1.7 ± 0.4 | 0.023 |
| 4 | 3.5 ± 0.7 | 7.6 |
| 5 | 2.6 ± 0.5 | 0.047 |
Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.