Table 1.

PTP1B and PTP1B-D181A proteins inhibit the growth of p210 bcr-abl-transformed cells in soft agar

Construct	No. of colonies per 104 cells		Acidification	No. of colonies per 104 cells	Acidification
	Rat-1	Rat-1/p210		Rat-1v-Abl
Vector	2.0 ± 1.2	A 676 ± 30	++	1732  ± 71	++
		B 669 ± 17	++
PTP1B	1.5 ± 1.1	A 265 ± 10	−	1826  ± 65	++
		B 260 ± 19	−
PTP1B-D181A	1.8 ± 0.8	A 325 ± 26	−	1782  ± 40	++
		B 309 ± 17	−
TCPTP	0.5 ± 0.5	A 608 ± 23	++	1715  ± 54	++
		B 589 ± 9	++