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. 1998 Nov 24;95(24):14168–14172. doi: 10.1073/pnas.95.24.14168

Figure 5.

Figure 5

DNA laddering analysis of adipose tissue DNA from insulin-depleted obese mice. (A) Genomic DNA was isolated from adipose tissue of control (3, 4) or anti-insulin antibody treated (1, 2) C57BL6 ob/ob mice described in Fig. 2A. (B). Male C57BL/6J ob/ob mice were injected with 200 mg/kg streptozotocin (2) or saline vehicle (1) as an i.v. bolus in 100 μl, adipose tissue was excised after 24 hr, and genomic DNA was prepared. DNA ladder was visualized by Southern blot analysis with a total mouse DNA probe.