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. Author manuscript; available in PMC: 2008 Jun 20.
Published in final edited form as: Mol Cell Proteomics. 2007 Oct 15;6(12):2212–2229. doi: 10.1074/mcp.M700354-MCP200

Fig. 3. Extracted ion chromatograms (A–C) and MRM spectra (D–F) of transitions monitored for mouse leptin in buffer (A and D), IgY-12 (B and E), and MARS hu7 (C and F) depleted plasma.

Fig. 3

Overlay of XICs and the corresponding MRM spectra for the three transitions monitored for INDISH-TQSVSAK peptide of leptin in 0.1% formic acid (A and D) and the same peptide produced by digestion of leptin protein that had been spiked at 25 ng/ml into IgY-12 depleted plasma (B and E) and into MARS hu7 depleted plasma (C and F). XICs and ions in the MRM/MS spectra are color-coordinated. cps, counts/s.