Fig. 3.
Structure of RepE initiator protein from F factor, a protein structurally similar to RepA of pSC101. The Glu at position 93 (E93) of RepE is identical to RepA. The side chain of E93 is circled and is located in β2b, a β-sheet important for protein dimerization. The structure of RepE (Diaz-Lopez et al., 2003) was obtained from PDB file 1REP and imaged with the program Cn3D. Helical regions are represented as cylinders and β-sheets as ribbons. The initiator protein is shown contacting DNA.