Generation of K14-VE-statin/egfl7 transgenic mice. (A) Graphic representation of the K14-VE-statin/egfl7 transgene: S, signal peptide; EMI, EMI domain; EGF, EGF-like domains; HA, haemaglutinin influenza tag epitope. (B) Immunostaining for VE-statin/egfl7 of skin section of wild type (WT, top panels) or P5 transgenic (bottom panels). Details of the tail skin immunostained with anti-VE-statin/egfl7 (left panels) or anti-HA antibodies (right panels). Arrows indicate VE-statin/egfl7-expressing keratinocytes (scale bar, 50 μm).