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. 2008 May 22;27(12):1658–1670. doi: 10.1038/emboj.2008.103

Figure 9.

Figure 9

VE-statin/egfl7 indirectly represses tropoelastin transcription. (A) RT–PCR analysis of tropoelastin and LOX transcripts in HUVEC cells transfected with control- (siRNA ctrl) or VE-statin/egfl7- (siRNA VE-statin) siRNA. (B) Immunolocalization of LoxL2 in HUVEC cells transfected with control- (siRNA ctrl) or VE-statin/egfl7- (siRNA VE-statin) siRNA. (C) Quantitative RT–PCR analysis of tropoelastin expression in HUVEC cells transfected with control- (siRNA ctrl) or VE-statin/egfl7-siRNA (siRNA VE-statin) and treated with BAPN or in HUVEC cells transfected with both VE-statin/egfl7-siRNA and two distinct LoxL2- siRNA (siRNA LoxL2 nos. 1 and 2). Reactions were performed in triplicate. Results are expressed as mean of relative quantity±s.d.