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. 2008 Jun 16;14:1157–1170.

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This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Mutation analysis of γ-crystallin genes. A: Family CCW-33 shows an R168W mutation in CRYGC. B: Family CCW-45 shows an R140X mutation in CRYGD. C: Family CCW47 shows a S39C mutation in CRYGS. D: RFLP analysis of CRYGS exon 1 shows the loss of HpyF10VI site (mutant allele-274 bp and 204 bp, wild-type allele-478 bp). E: Individual V:3 of family CCW47 shows sutural cataract. F: Individual II:1 of family CCW33 shows lamellar cataract. M denotes 100 bp DNA ladder, and C denotes unrelated control.