FIG. 6.

Statistical power to distinguish between two injury severities in terms of hidden platform water maze performance. Monte-Carlo simulations were used based on original data sets from the 22 mice in the 2.0-mm and 3.0-mm impact groups. 150 random subsamples of these 22 mice were reanalyzed using repeated-measures ANOVA. For this analysis, the total number of mice in the random subsamples is plotted on the x-axis. The median and 80% confidence interval of the resulting p-values are plotted on the y-axis. This analysis indicates that, with 15 or greater total mice in the two groups, we would expect at least an 80% likelihood of detecting a difference between groups with a p-value of <0.05.