Table 3.
Statistical analysis of the response of DEVDase to PDT in SMS1 siRNA- and SMS2 siRNA-transfectants compared to scrambled (control) siRNA-transfectants.
| FCG | FCD | pGroupFDR | pDoseFDR | |
|---|---|---|---|---|
| SMS1 siRNA | 1.65 | 1.94 | 1.48E-05 | 1.03E-11 |
| SMS2 siRNA | 1.53 | 1.61 | 1.08E-04 | 2.76E-06 |
The FCG is the estimated fold-change between SMS1 siRNA-transfectants and their corresponding controls, or between SMS2 siRNA-transfectants and their corresponding controls regarding the DEVDase response, assuming a constant PDT dose. The FCD is the estimated fold-change in response to each 100 units of dose (light fluence), regardless of the group (cell type). The pGroupFDR and the pDoseFDR are corresponding adjusted p-values using false discovery rate algorithm. Bold type indicates statistical significance.