Table 1.
Distribution of mean AIMS score according to genotype in patients with TD.
Polymorphism# | AIMS score (mean±SD) | p-value* | ||
---|---|---|---|---|
11 | 12 | 22 | ||
SOD2
Ala9Val C/T |
7.12±4.16 | 6.17±3.29 | 5.67±2.89 | 0.436 |
UCP2
45bp del/ins |
6.35±3.21 | 5.93±3.70 | -- | 0.287 |
NOS1 rs1047735
C/T |
6.12±3.43 | 5.76±2.96 | 7.00±3.63 | 0.730 |
NOS1 rs2682826
C/T |
5.84±3.24 | 6.03±3.40 | 7.17±3.43 | 0.591 |
NOS3
27bp ins/dup |
6.81±3.63 | 5.13±3.20 | 7.50±2.12 | 0.038 |
GSTM1
Presence/Null |
6.00±3.29 | 6.33±3.46 | 0.643 | |
GSTT1
Presence/Null |
6.27±5.27 | 5.27±2.28 | 0.580 | |
GSTPI
Ile105Val A/G |
5.68±2.57 | 6.49±3.63 | 6.11±4.51 | 0.595 |
NQO1
Pro187Ser C/T |
6.20±3.40 | 6.80±3.40 | 3.57±0.54 | 0.061ψ |
The 11 genotype corresponds to the first allele e.g. Ala9Val C/T 11=CC, 12=CT,22=TT genotypes;
Kruksal Wallis H test;
CC+CT vs TT 6.42 ± 3.44 vs. 3.57 ± 0.54; p=0.025