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. Author manuscript; available in PMC: 2008 Jun 21.
Published in final edited form as: Mech Dev. 2007 Feb 21;124(5):350–363. doi: 10.1016/j.mod.2007.02.001

Figure 2.

Figure 2

Ventralization caused by fatvg-depletion is reminiscent of UV irradiation and β-catenin-depleted embryos but different than VegT depleted embryos. (A) fatvg-depleted embryos showing a class III phenotype with a complete loss of axial identity. (B) β-catenin-depleted embryos showing a similar phenotype. (C) Embryos that had been irradiated at the vegetal pole after fertilization. (D) VegT-depleted embryos are defective in endoderm and mesoderm formation. The two bottom embryos show the most severe phenotype of VegT depletion in which only epidermal development is apparent. (E) Embryos injected with 2ng BMP-4 at 2-cell stage. (F) Control embryo at stage 39.