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Comparison of feature extraction by manual vs. automated segmentation of dual-axis SIRT reconstructed HIV-1 tomogram. (A) unprocessed and (B) denoised tomogram visualized in the environment of Amira. (C) & (D) Comparison of “single-click” segmentation results for unprocessed and denoised tomograms respectively, with denoising performed using the phase-preserving algorithm.
