Figure 3.

Compared to IFN-α, IFN-λ prolongs ISG expression in HaCaT cells. Cells were treated with either IFN-α (5 ng/mL) or IFN-λ (100 ng/mL) for the indicated times. Expression of the ISGs: ISG15, MX-1, TRAIL, SOCS1, and SOCS3 were determined by qRT-PCR. Results are presented as the relative fold induction and this is a representative experiment of 3 that were performed. Samples were normalized using the 18S ribosomal subunit.