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. Author manuscript; available in PMC: 2009 Mar 1.
Published in final edited form as: Clin Chest Med. 2008 Mar;29(1):195–vii. doi: 10.1016/j.ccm.2007.12.003

Figure 10.

Figure 10

Examples of hyperpolarized 3-Helium MRI and correlation with HRCT. A, B Patient with alpha-1-antitrypsin deficiency. Notice basal ventilation defects on coronal MRI (a), with corresponding panlobular emphysema on axial CT (b). C, D Patient with cystic fibrosis. Notice upper lobe cystic bronchiectasis on axial HRCT (C) with corresponding ventilation defects on coronal hyperpolarized 3-He MRI (D). E,F Patient with lung cancer. On coronal proton image a large soft tissue mass is visualized in the right upper lung(E), which corresponds to upper lobe ventilation defect on hyperpolarized 3-He MRI (F).