Table 2.

Bisphosphonate use and risk of ONJ.

	Crude		Adjusted†
Bisphosphonate	Odds Ratio	95% C.I	Odds Ratio	95% C.I
IV Bisphosphonate	4.23*	2.21 – 6.25	29.77*	1.20 – 733.91
Pamidronate‡: yes	3.85*	1.41 – 10.51	2.88	0.59 – 14.03
per mg	1.00	0.99 – 1.00	1.00	0.99 – 1.00
per month	1.02	0.99 – 1.04	1.01	0.97 – 1.06
per infusion	1.02	1.00 – 1.05	1.02	0.98 – 1.07
Zoledronate: yes	71.16*	9.47 – 534.88	31.82*	1.75 – 579.33
per mg	1.03*	1.02 – 1.04	1.04*	1.01 – 1.06
per month	1.10*	1.05 – 1.15	1.09*	1.02 – 1.17
per infusion	1.12*	1.06 – 1.17	1.11*	1.03 – 1.20
Oral Bisphosphonates	0.33	0.07 – 1.65	1.26	0.11 – 14.86

^*p<0.05

^†adjusted for metastasis, obesity, and smoking

^‡further adjusted for zoledronate