Table 4.

Comorbidities and risk of ONJ.

	Crude		Adjusted†
Comorbidities	Odds Ratio	95% C.I	Odds Ratio	95% C.I
Alcohol Abuse	3.75	0.84 – 16.76	0.13	0.00 – 10.22
Asthma	1.73	0.60 – 5.00	1.17	0.18 – 7.55
Deep Vein Thrombosis	2.14	0.55 – 8.29	0.33	0.02 – 6.66
Diabetes	2.26	0.88 – 5.84	1.68	0.40 – 6.99
Gastric Reflux	0.94	0.39 – 2.25	0.92	0.17 – 4.97
Hypercholesterolemia	1.32	0.54 – 3.23	1.50	0.33 – 6.83
Hypertension	1.74	0.74 – 4.08	1.17	0.31 – 4.37
Obesity	4.02*	1.79 – 9.03	16.61*	1.80 – 153.71
Osteoporosis	0.70	0.21 – 2.35	2.26	0.29 – 17.65
Smoking: yes	5.94*	2.28 – 15.49	7.41*	1.28 – 43.10
per pack year	1.04*	1.01 – 1.06	1.03	0.97 – 1.10
Metastasis	41.09*	5.35 – 315.38	27.39*	0.99 – 757.40

^*p<0.05

^†adjusted for metastasis, zoledronate, obesity, and smoking