Skip to main content
. Author manuscript; available in PMC: 2008 Dec 18.
Published in final edited form as: Biochemistry. 2007 Nov 20;46(50):14349–14358. doi: 10.1021/bi701202w

Figure 10.

Figure 10

Treatment of isogenic strains of S. aureus with a mixture of Fraction 2 globins indicates the two component system SrrA-SrrB is targeted by the proteins. Data compared production of TSST-1 (production regulated by SrrA-SrrB) by the tested strains. RN4220 (pJMY10) contains the chromosomally-encoded two component system SrrA-SrrB that functions as a repressor of exotoxin production under low oxygen conditions (20), and the organism contains the gene for TSST-1 production on a plasmid (open boxes). Strain MN4010 is an isogenic organism that lacks a functional SrrB gene; the organism contains the gene for TSST-1 on the same plasmid (filled boxes).