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. Author manuscript; available in PMC: 2009 May 15.
Published in final edited form as: J Immunol. 2008 May 15;180(10):6566–6576. doi: 10.4049/jimmunol.180.10.6566

FIGURE 4.

FIGURE 4

Hyporesponsive T cells generated upon co-stimulation by CD80 exhibit regulatory properties. Co-stimulation blockade assay was carried out as described for Fig. 1. CD4+ T cells from this culture were incubated with OVA pulsed APCs and CFSE labeled total T cells from OVA primed mice (effector cells) for additional 5 days, stained with PE labeled anti-CD4 or CD8 Abs, and examined for CFSE dilution in effector populations. Representative values are shown. This assay was repeated at least 4 times with similar results. * indicates a p value of <0.05.