Table 3.
Cognitive Construct | Task | Dependent Variable | Age Group | 2.5 µg/kg SCOP + E2 | 2.5 µg/kg SCOP + PLC | 20 mg MECA + E2 | 20 mg MECA + PLC |
---|---|---|---|---|---|---|---|
Attention | |||||||
CFF | |||||||
Total (Hz) | Young | −.76 (.73) | −1.45 (.52) | 1.77 (1.05) | .81 (.51) | ||
Old | −.72 (.76) | −.62 (.52) | 1.39 (1.05) | 1.11 (.54) | |||
Ascending (Hz) | Young | −.55 (.96) | −1.03 (.60) | 1.37 (.60) | .28 (.60) | ||
Old | .31 (1.0) | −.42 (.60) | .33 (.60) | .88 (.63) | |||
Descending (Hz) | Young | −1.35 (.62) | −1.54 (.62) | .44 (.55) | .26 (.55) | ||
Old | −1.47 (.62) | −1.04 (.62) | .35 (.55) | .47 (.58) | |||
CRT | |||||||
Total (ms) | Young | 43.73 (26.1) | 22.95 (26.1) | 11.31 (25.9) | 39.23 (25.5) | ||
Old | 39.56 (26.1) | 65.51 (26.1) | 86.51 (25.9) | 30.32 (25.8) | |||
Recognition RT (ms) | Young | 11.83 (15.5) | 19.64 (15.5) | 2.53 (12.0) | −1.75 (14.2) | ||
Old | 16.37 (15.5) | 41.24 (15.5) | −15.56 (13.4) | −1.44 (12.6) | |||
Motor RT (ms) | Young | 18.24 (20.2) | −8.77 (20.2) | 14.38 (20.1) | 25.07 (20.1) | ||
Old | −5.35 (20.2) | 16.81 (20.2) | 61.03 (20.1) | 29.56 (20.1) | |||
CPT | |||||||
Hits (proportion correct) | Young | −2.89 (2.4) | −5.18 (1.5) | −.01 (1.38) | −.55 (.4) | ||
Old | .86 (2.4) | −1.49 (1.5) | 0.82 (1.26) | .18 (0.4) | |||
Errors of Omission (number of errors) | Young | 2.89 (2.4) | 4.91 (1.5) | −.21 (1.4) | .55 (.4) | ||
Old | −.89 (2.4) | 1.58(1.5) | −.91 (1.3) | −.18 (.4) | |||
Errors of Comission (number of errors) | Young | 1.3 (0.5) | .91 (.5) | .85 (.4) | −.27 (.3) | ||
Old | .10 (0.5) | 1.10 (.5) | −.27 (.3) | .18 (.3) | |||
Hit RT (ms) | Young | 52.49 (18.2) | 12.29 (17.3) | 22.46 (19.3) | 18.99 (17.4) | ||
Old | −14.49 (18.2) | −43.90 (18.2) | 7.78 (17.4) | −8.48 (17.4) | |||
Verbal Memory | |||||||
SRT | |||||||
Total Recall (number correct)1 | Young | −13.55 (3.6) | −20.00 (3.6) | −2.64 (2.7) | −7.18 (2.7) | ||
Old | −16.00 (3.6) | −7.55 (3.6) | −5.73 (2.7) | −2.55 (2.7) | |||
Recall Consistency (number correct)2 | Young | −11.91 (3.6) | −19.9 (3.6) | −1.45 (3.1) | −8.36 (3.1) | ||
Old | −15.73 (3.6) | −5.73 (3.6) | −6.54 (3.1) | −2.18 (3.1) | |||
Recall Failure (number of failures)3 | Young | 11.08 (2.9) | 16.82 (4.1) | 3.01 (2.4) | 3.73 (2.4) | ||
Old | 13.00 (2.9) | 7.00 (4.1) | 3.36 (2.4) | 3.00 (2.4) | |||
PR | |||||||
NYU Scoring (number correct) | Young | −.15 (0.04) | −.05 (.07) | −.05 (0.1) | .01 (.1) | ||
Old | −.02 (0.04) | .05 (.07) | .003 (.1) | .07 (0.1) |
SCOP analysis age and treatment interaction for total recall: F(1,20) = 10.73, p < .01
SCOP analysis age and treatment interaction for recall consistency: F(1,20) = 17.44, p < .001
SCOP analysis age and treatment interaction for recall failure: F(1,20) = 5.57, p < .05