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. Author manuscript; available in PMC: 2009 May 1.
Published in final edited form as: Dev Biol. 2008 Feb 21;317(1):187–195. doi: 10.1016/j.ydbio.2008.02.017

Figure 2.

Figure 2

AP-2γ mutant skin shows delayed expression of proteins involved in epidermal differentiation. Skin samples from control (A, C, E, G, I and K) and AP-2γ mutant (B, D, F, H, J and L) embryos were sectioned and stained with antibodies specific for epidermal development markers. A, B, E and F) p63 and K14 were detected in control but not in mutant skin at E11.5 but were detected in mutant skin at E16.5. G, H, K and L) K1 was detected in control skin at E16.5 but not in AP-2γ mutant skin. K1 expression was detected in the AP-2γ mutant skin at E18.5. C, D, I, and J) H&E staining shows a lack of stratification in mutant samples compared to controls at both E11.5 and E16.5.