Figure 3.

Expression profiles of genes involved in the main metabolic networks of S. cerevisiae. Transcription factors are presented with boldfacing and connected to the respective target genes with gray lines. The connections shown between transcription factors and their target genes are based on compilations in Yeast Proteome Database [70][80] and on the transcription factor binding network by Young and co-workers [82]. Expression of the genes presented in white boxes with black text was highest in the glucose derepressed cells (Derep.) and lowest in the glucose repressed cells (Rep.). Expression of the genes presented in black boxes with white text was highest in the glucose repressed cells and lowest in the glucose derepressed cells. Expression of the genes presented in dark gray boxes with black text was highest in the xylose-grown cells and lowest in the glucose derepressed cells. Expression of the genes presented in light gray boxes with black text was highest in the xylose-grown cells and lowest in the glucose repressed cells. Expression of the genes presented in gray boxes with white text was lowest in the xylose-grown cells. In addition to the genes shown in the figure, 89% of the genes (31 out of 35) annotated to GO category "Oxidative phosphorylation" and its daughter categories [33] had highest expression in the glucose derepressed cells, lowest expression in the glucose repressed cells and intermediate expression in the cells grown on xylose (data not shown).