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Contents of thiamine, ThMP, ThDP and total thiamine in the liver and the brain of mice (strain sv129) after daily oral administration of 200 mM HP-β-CD (8 animals) or benfotiamine (100 mg/kg) in approximately 100 μl of a 200 HP-β-CD solution (10 animals) for 14 days. The data (mean ± SEM) were analyzed by MANOVA (Liver : Wilk's Lambda = 0.24, p = 0.0061; Brain : Wilk's Lambda = 0.779, p = 0.48) followed by an ANOVA for each thiamine compound (*, p < 0.05; **, p < 0.01).
