Table 2.
Numbers of Macrophages, Mast cells and Neutrophils in lung tissue from COPD patients and individuals with normal lung function
| Normal lung Function (4M/6F) | GOLD I/II (6M/4F) | p Value | |
| Lung function (FEV1/FVC) | 0.79 ± 0.02 | 0.62 ± 0.03 | 0.05 |
| FEV1 % predicted | 99.2 ± 9.7 | 77.2 ± 8.5 | 0.05 |
| Smoking status | 4 current smokers | 4 current smokers | |
| 3 ex-smokers | 5 ex-smokers | ||
| 2 non-smokers | |||
| Age | 64.7. ± 7.9 | 71.2 ± 2.0 | 0.07 |
| Macrophage (CD68) cell/mm2 | 2.8 ± 0.6 | 5.4 ± 1.4 | 0.10 |
| Mast Cell (Tryptase) cell/mm2 | 20.6 ± 5.5 | 17.1 ± 3.9 | 0.23 |
| Neutrophil (Neutrophil elastase) cell/mm2 | 8.1 ± 0.7 | 11.5 ± 3.6 | 0.15 |
Patient data including lung function given as the ratio of air that can be forcibly exhaled in one second (FEV1) to the forced vital capacity (FVC), FEV1/FVC and FEV1% predicted, smoking status, age and gender are listed as the mean ± SEM. Cell numbers are listed as the mean number of cells/mm2, ± SEM and the p value obtained when comparing the each factor between the two groups is given, p < 0.05 was considered statistically significant.