Table 2.

Examples of quorum-quenching molecules against microbial infections.

quorum-quenching molecules		host	effect	reference
AHL-lactonase	aiiA	Erwinia carotovora	decreases extracellular pectolytic enzyme activities, and attenuates soft rot symptom on the plants inoculated	Dong et al. (2000)
		tobacco, potato	transgenic plants are resistant to E. carotovora infection	Dong et al. (2001)
		Pseudomonas aeruginosa	decreases production of elastase, rhamnolipids, hydrogen cyanide and pyocyanin, and inhibits bacterial swarming	Reimmann et al. (2002)
		Escherichia coli	attenuates the pathogenicity of E. carotovora when co-inoculated	Lee et al. (2002)
		Bacillus thuringiensis	the efficiency of biocontrol against E. carotovora infection is dependent on AHL-lactonase	Dong et al. (2004)
		Burkholderia thailandensis	reduces the bacterial swarming and twitching motility, prevents the β-haemolysis of sheep erythrocytes	Ulrich (2004)
		Erwinia amylovora	impairs extracellular polysaccharide production and tolerance to hydrogen peroxide, and reduces the fire blight symptom on apple leaves	Molina et al. (2005)
	attM, aiiB	Erwinia carotovora subsp. Atroseptica	decreases maceration in potato tubers	Carlier et al. (2003)
paraoxonase	PON1	P. aeruginosa	the serum containing PON1 prevents bacterial biofilm formation in vitro	Ozer et al. (2005)
AHL-acylase	aiiD	P. aeruginosa	decreases swarming ability, elastase and pyocyanin production, and attenuates nematode paralysation	Lin et al. (2003)
synthetic AIP-II		mouse	treated mice show resistance to S. aureus infection	Mayville et al. (1999)
3-oxo-C12-(2-aminocyclohexanone)		P. aeruginosa	reduces the production of virulence factors and biofilm formation	Smith et al. (2003)
furanone		mouse	attenuates the virulence of P. aeruginosa in mouse models	Hentzer et al. (2003)
DSF		Candida albicans	inhibits the fungal dimorphic transition that is associated with virulence	Wang et al. (2004)