Table 3.

Participant flow and timeline from screening to randomization

Timeline	Action	Participant Data Collected		Purpose
Week 1	Telephone Screen	Demographic information Self-reported medical information to screen		To determine initial illegibility
Week 2	Orientation & CRP Screening	Informed consent Measurements: height, weight Blood chemistry screening: CRP		To ensure that the participant understands the expectations of the study and meets inclusion criteria
Week 3–4	3 Educational Run-In Sessions	Questionnaires: FFQ, medication inventory, detailed medical history Measurements: BP Behavioral Contract		To ensure participant meets inclusion criteria and can visit the intervention site multiple times per week
Week 5	Baseline Evaluations	Blood draw Measurements: ECG, CT scan, DXA, height, weight, waist and hip circumference Fitness Testing		Collect baseline data and ensure participant meet remaining study entry criteria
Week 6	Randomization
Week 7–23	Intervention	Exercise Group: Exercise 3–5x per wk Self-reported data returned monthlya	Control Group: Self-reported data returned monthlya	Collect intervention data as well as data on potential confounding variables such as health, diet and non-study related activity
Week 24	Follow-Up Evaluations	Blood draw Measurements: EBT, DXA, height, weight, waist and hip circumference, BMI, BP Fitness Testing Questionnaires: FFQ, MSQ, Exit Interview		Collect follow-up data

^aSelf Report Data Returned Monthly includes: Medical Symptoms Questionnaire, Medication Inventory and Daily Step Log