Table 4.
Characteristics of nonobese subjects
| Characteristics | Controls (n = 45) | OCP users (n = 14) | P valuesa |
|---|---|---|---|
| Age (yr) | 34.6 ± 8.1 | 29.7 ± 6.8 | 0.05 |
| BMI (kg/m2) | 25.1 ± 2.8 | 24.3 ± 3.7 | 0.37 |
| Body fat (%) | 31.4 ± 5.6 | 28.8 ± 5.6 | 0.13 |
| Current smokers | 7% | 7% | 0.95b |
| Alcohol intake of ≤ 1 drink per wk | 80% | 57% | 0.09b |
| Regular physical activityc | 33% | 43% | 0.52b |
| Family history of DM | 49% | 50% | 0.94b |
| Prevalence of IGT | 9% | 36% | 0.01b |
| Fasting insulin (μU/ml) | 6.1 ± 2.4 | 7.6 ± 2.2 | 0.05 |
| Fasting glucose (mg/dl) | 82 ± 6 | 80.3 ± 6.8 | 0.40 |
| 2-h glucose (mg/dl) | 112 ± 22 | 130 ± 22.5 | 0.01 |
| SI (liter/mU−1·min−1)d | 4.35 ± 1.88 | 2.91 ± 1.58 | 0.03 |
| AIRg (mU/liter−1·min)d | 667. ± 347 | 658.4 ± 387.6 | 0.95 |
| DId | 2657.8 ± 1529.5 | 1616 ± 718 | 0.04 |
| Total cholesterol (mg/dl) | 162 ± 30 | 177 ± 35 | 0.12 |
| TGs (mg/dl) | 49 ± 19 | 75 ± 34 | <0.01 |
| HDL-cholesterol (mg/dl) | 54 ± 11 | 65 ± 13 | <0.01 |
| LDL-cholesterol (mg/dl) | 98 ± 27 | 96 ± 29 | 0.86 |
| SHBG (nmol/liter) | 52.5 ± 25.7 | 138.8 ± 66.8 | <0.01 |
| Estradiol (pg/ml) | 84.2 ± 63.6 | 48.6.4 ± 87.1 | <0.01 |
Data are presented as mean ± sd. DM, Diabetes mellitus; IGT, impaired glucose tolerance.
a
Unless otherwise stated, comparisons were by the t test.
b
Analyses by the χ2 test.
c
Physical activity is defined as participating in recreational/fitness activity such as jogging, swimming, or cycling for at least three times per week for 30–60 min each time.
d
Data in 42 subjects (32 controls, 10 OCP users).