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. 2008 Mar 18;93(6):2109–2114. doi: 10.1210/jc.2007-2266

Table 2.

GH use, body composition, and glucose tolerance in TS

GH (76) No GH (26) P
Age (yr) 13.9 ± 3.6 13.6 ± 3.7 NS
BMI (kg/m2) 22.2 ± 4.7 25.1 ± 7.2 0.002a
Height sd -1.93 ± 0.8 −2.51 ± 1.3 0.009a
BF (%) 28.2 ± 8.3 35 ± 7.7 P < 0.0001b
SAT (ml)c 99.5 ± 81.8 183.2 ± 37.5 0.001b
VAT (ml)c 33 ± 13.7 49.8 ± 7.8 0.0009b
IGT 7% 28% 0.006

SAT and VAT were measured by MRI. IGT indicates blood glucose more than 140 mg/dl on oral glucose tolerance test. Data are means ± sd or proportion. Prevalence of IGT was compared by χ 2. GH was not administered the day before or day of metabolic testing. P values remain significant at P < 0.01 after Bonferroni correction. BF, Total body fat measured by DXA. 

a

Group means were compared by ANCOVA including age as covariate. 

b

Group means were compared by ANCOVA including age and BMI as covariates. 

c

Fifty-two GH-treated and 17 untreated girls had MRI abdominal fat measurements.