Table 3.
Prepubertal GH treatment, body composition, and glucose tolerance
| GH (36) | No GH (18) | P | |
|---|---|---|---|
| Age (yr) | 10.7 ± 03.4 (7–16) | 12.5 ± 2.8 (7–16) | 0.02 |
| BMI (kg/m2) | 20.3 ± 3.7 | 23.2 ± 4.1 | 0.01a |
| BF (%) | 24.6 ± 3.2 | 34.4 ± 4.5 | <0.0001b |
| SAT (ml)c | 70.3 ± 12.3 | 112.0 ± 21.8 | 0.0003b |
| VAT (ml)c | 29.9 ± 7.0 | 35.9 ± 6.6 | 0.19b |
| IGT | 0 | 5/17 | 0.001 |
These data are for girls currently on GH. Data are means ± se. IGT was compared by χ 2.
a
Group means were compared by ANCOVA including age as covariate.
b
Group means were compared by ANCOVA including age and BMI as covariates.
c
There were 24 GH-treated and 11 untreated girls that had MRI abdominal fat measurements