Table 4.
Mixed-effects modeling of baseline and change in LH
| Factor | Effect | se | P |
|---|---|---|---|
| Baseline LH as outcome | |||
| Insulin | −0.719 | 0.0589 | NS |
| PCOS | 4.328 | 2.616 | NS |
| GnRH Dose | 0.143 | 0.027 | <0.0001 |
| BMI | −0.268 | 0.089 | 0.008 |
| T | 2.757 | 1.364 | 0.06 |
| Insulin × PCOS | −3.106 | 0.795 | 0.0002 |
| Peak vs. Baseline LH as Outcome | |||
| Insulin | −1.566 | 1.109 | NS |
| PCOS | −10.550 | 8.046 | NS |
| GnRH Dose | 0.013 | 0.073 | NS |
| BMI | 0.329 | 0.282 | NS |
| T | 6.122 | 4.276 | NS |
| Baseline LH | 1.958 | 0.222 | <0.0001 |
Factors testing significant in multivariable models above were utilized in mixed effects models testing significance under insulin infusion and GnRH dosing. Factors not shown did not show significance in either outcome tested. NS = Not significant.