Figure 3.

Disruption of Drosophila eye development by expression of pep4 and pep8 Cdk aptamers. Scanning electron micrographs of adult Drosophila eyes developed from larvae exposed to heat shock as in Table 1, protocol 4. (A and B) Heat-shocked control hs-pepC2 (Line 1) fly showing the typical wild-type organized array of ommatidia. (C and D) A typical rough eye from a heat-shocked hs-pep4 (Line 2) fly. (E and F) A case of severe deformation of an eye from a heat-shocked hs-pep8 (Line 2) fly. (A, C, and E, ×100; B, D, and F, ×500.)