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The mutation of clone 49 at position 45 restores binding to HLA-Cw7. HLA-Cw7 (5.8 μM) was injected over NKAT2 (456 RU), clone 49 (673 RU), and the two mutants of clone 49 Y45F (669 RU) and E35Q (1028 RU). These data are representative of multiple experiments.
