Figure 4.

The kinetics of the 3.L2 response is unaltered in the presence of endogenous A72. 3.L2tg splenocytes were adoptively transferred to A72tg⁺ mice and A72tg⁻ littermates as described. All mice were immunized on the following day with 2 nmol of Hb(64–76) peptide emulsified in CFA, and pairs of mice were sacrificed on days 3–8 postimmunization. The percentage of CD4⁺ T cells that are CAB⁺ in draining lymph nodes was quantitated by FACS on the indicated days and plotted as a function of time. The data shown are representative of three similar time course experiments.