Table 1.

Summary data of functional responses to NKA in porcine mucosal strips

Agonist	Inhibitor (concentration)		pD2	Emax at 10 μM (% maximal carbachol)	n
NKA	—	—	7.2±0.2	98.8±12.0	12
[Lys5,MeLeu9,Nle10]NKA(4–10)	—	—	7.9±0.1	105.2±5.0	6
NKA	TTX	1 μM	7.8±0.1	95.1±4.5	8
NKA	Indomethacin	1 μM	7.8±0.1	108.0±4.7	8
NKA	SR140333	1 μM	7.5±0.2	97.6±5.2	5
		1 nM	6.6±0.3	94.2±7.7	5
NKA	SR48968	3 nM	5.9±0.2**	72.8±11.7	6
		10 nM	5.5±0.4**	36.8±11.0**	4

Abbreviations: NKA, neurokinin A; TTX, tetrodotoxin.

^**P<0.01 (ANOVA followed by Dunnett's test).