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. 2008 Feb 4;153(7):1388–1398. doi: 10.1038/bjp.2008.8

Figure 3.

Figure 3

Typical records showing effect of pioglitazone on vasoconstrictor responses to spinal cord stimulation (SCS) (A, D and G; 2–8 Hz; triangles) and bolus injections of noradrenaline (NA) (B, E and H; 125–500 ng kg−1; circles) and angiotensin II (Ang II) (C, F and I; 40–200 pmol kg−1; squares) in the pithed control rats (upper trace), untreated fructose-drinking rats (FDR; middle trace) and pioglitazone (PIO)-treated FDR (lower trace). PIO at a dose of 10 mg kg−1 day−1 was administered p.o. for 2 weeks from 14 to 16 weeks of age.