Figure 2.
Stable transduction of C2C12 myoblasts with AAV-AAT vectors in vitro. The mean rates of secretion from G418-resistant cultures 1 mo after transduction with either packaged E-AT vector or packaged C-AT vector are shown. In each instance, a “low” multiplicity transduction (4 × 105 particles/cell) and a high multiplicity transduction (4 × 106 particles/cell) were performed. E-AT “low” and “high” are greater than “high” multiplicity C-AT (P = 0.02) but are not significantly different from each other (n = 3).