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. 2008 May 14;105(20):7235–7239. doi: 10.1073/pnas.0802301105

Fig. 6.

Fig. 6.

Functional analyses of the Opn-i isoform: ifna4 promoter activation and podosome formation. (A) Opn expression and ifna4 activation in 293FT cells transiently transfected with increasing concentrations of Opn expression vectors along with IRF7 and MyD88, as described (12). (B) Opn WT and KO pDC were not infected or were infected with the indicated Opn lentiviral constructs. Proportions of pDC with long (length of podosome > cell diameter; gray) and short (length of podosome < cell diameter; black) podosomes were calculated from total 120 cells per sample.