Figure 7.
Leukocyte transmigration in haemorrhagic shock-induced, I/R-activated rat mesenteric venules. Rats subjected to I/R showed increased leukocyte transmigration in the mesenteric microvasculature. Transmigration was significantly inhibited by pretreatment with 10 mg kg−1 cariporide. Values are means±s.e.mean. Asterisks indicate a significant difference from the time-matched I/R plus vehicle group, where *P<0.05 and **P<0.01. There were 6–10 rats in each group. I/R, ischaemia/reperfusion.