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. 2008 Jul;173(1):30–41. doi: 10.2353/ajpath.2008.070583

Figure 2.

Figure 2

HGF inhibits renal infiltration of inflammatory F4/80-positive macrophages. A–E: Immunohistochemical staining revealed an increased infiltration of F4/80-positive macrophages in the obstructed kidney at 7 (B) and 14 (D) days, respectively, after UUO, compared with sham control (A). Delivery of HGF gene effectively inhibited the infiltration of macrophages in the obstructed kidneys at 7 (C) and 14 (E) days after UUO, respectively, as indicated. F: Graphic presentation of quantitative data are given. Data were presented as mean ± SEM of five animals per group (n = 5). *P < 0.01 versus sham control. †P < 0.01 versus pcDNA3. Scale bar = 20 μm.