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. 2008 May 26;5:20. doi: 10.1186/1742-2094-5-20

Table 7.

Summary of the expression of genes of the cholesterol biosynthesis within the spinal cord during EAE

Affymetrix ID Gene Title Gene Symbol mean healthy mean acute mean recovery mean relapsing
U36992_at cytochrome P450, subfamily 7B, polypeptide 1 Cyp7b1 98.59 195.80 276.35 162.86
rc_AI171090_at 3-hydroxy-3-methylglutaryl CoA lyase Hmgcl 202.20 227.46 239.53 261.08
rc_AI171090_g_at 54.98 105.97 67.11 72.45
rc_AA945052_at 102.85 198.26 202.62 199.80
M33648_at 3-hydroxy-3-methylglutaryl-Coenzyme A synthase 2 Hmgcs2 138.44 148.71 172.73 176.42
M33648_g_at 53.88 71.08 127.08 89.43
M29472_at mevalonate kinase Mvk 579.91 347.12 365.24 334.64
rc_AA924198_s_at 89.59 30.12 42.34 41.04
D45252_s_at 2,3-oxidosqualene: lanosterol cyclase Lss 133.77 96.43 52.29 62.71
U31352_at 78.55 43.51 25.09 30.56
U53706_at Di-P-Mevalonate Decarboxylase Mvd 337.31 275.95 170.16 249.65
rc_AI236566_at Geranyl-trans-transferase Gtt 539.00 251.35 431.77 336.83
rc_AI180442_at 73.18 30.33 24.05 30.71
M95591_at farnesyl diphosphate farnesyl transferase 1 Fdft1 361.69 140.36 10.93 57.25
M95591_g_at 177.78 63.88 14.50 37.18
rc_AA859392_s_at 150.44 60.54 12.54 29.40
rc_AI229016_s_at 683.89 363.56 292.72 350.46
D37920_at squalene monoxidase Sqle 454.41 196.60 217.42 194.23
rc_AA819300_at 106.60 47.75 40.46 44.46
AF003835_at isopentenyl-diphosphate delta isomerase Idi1 358.66 107.23 75.43 70.95
rc_AI236611_at 70.34 40.75 43.74 49.80
M29249cds_at 3-hydroxy-3-methylglutaryl-Coenzyme A reductase Hmgcr 88.42 27.52 2.90 10.18
rc_AA924210_at 274.91 136.54 79.63 86.09
X55286_at 29.11 11.75 1.63 5.22
X55286_g_at 49.36 24.45 7.98 12.30
AB016800_at 7-dehydrocholesterol reductase Dhcr7 173.32 60.96 86.66 80.03
AB016800_g_at 179.32 65.09 120.92 104.75
rc_AI177004_s_at 3-hydroxy-3-methylglutaryl-Coenzyme A synthase 1 Hmgcs1 741.89 171.63 86.91 96.25
X52625_at 1524.92 577.65 626.34 493.05
rc_AI043855_at sterol-C5-desaturase (fungal ERG3, delta-5-desaturase)-like Sc5d 435.08 141.91 79.75 124.68
AB004096_at cytochrome P450, subfamily 51 Cyp51 246.53 77.01 100.46 87.21