Figure 1.

Effect of Ad. Vec, Ad.β-gal, and Ad.mda-7 S on the growth of normal breast and breast cancer cells. The indicated cell types were infected with 100 pfu/cell of Ad.Vec, Ad.β-gal, or Ad.mda-7 S, and cell growth was determined over a 14-day period. Triplicate samples varied by ≤10%. Similar results (±15%) were obtained in two additional replicate studies. In the lower panels, β-galactosidase activity was assayed in HMEC (A), HBL-100 (B), T47D (C), and MCF-7 (D) cells 48 hr after infection with the Ad.β-gal.