Table 1.

Percentage of myotubes displaying normal or disrupted sarcomeres after CMV promoter-driven cardiac TnT expression

	% normal sarcomeres	% disrupted regions
Control	100	0
Wild-type cardiac TnT	100	0
Truncated TnT mutant	0	100
Ile79Asn mutant	92.5	7.5
Arg92Gln mutant	89	11
ΔGlu160 mutant	91	9

Numbers in this table are based on counts of 1,000 myotubes. The truncated TnT is described in ref. 8. It results from a splicing error that removes the C-terminal 28 amino acids and replaces them with seven incorrect amino acids.