Amino acid sequence of part of the HIV-1 envelope protein in patients 125, 127, 129, 134, and 224 from start of ritonavir therapy as compared with the sequence of HIV-1 consensus B. Pretherapy sequences are listed for the antiviral-therapy naive patients 125 and 127. Uppercase letters refer to an amino acid change that dominated the population, whereas heterogeneous amino acid positions are indicated with lowercase letters. Particular positions known to be involved in glycosylation (g), antigenicity (a), and phenotype (p) are indicated in gray.