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Proliferative activity in CD4 T cells. Peripheral T cells were isolated freshly from normal controls and RA patients, and the percentages of CD4 T cells in the S-G2/M phase were determined. Results are shown as box plots. Median, 25th, and 75th percentiles (box), and 10th and 90th percentiles (whiskers) are displayed. The fraction of CD4 T cells in the cell cycle was increased significantly in RA patients (P = 0.01).
