Skip to main content
. 1998 Nov 24;95(24):14453–14458. doi: 10.1073/pnas.95.24.14453

Figure 4.

Figure 4

Effect of p53 expression in D283 on BAX induction after irradiation. (A) Representative Northern blot analysis of BAX expression is shown. Total RNA prepared from D283 clones, mp53.1, mp53.3, and vec.1 at 0 (1), 6 (2), and 24 (3) hr after treatment with 5 Gy of ionizing radiation was examined by Northern blot analysis for expression of BAX and GAPDH mRNA. Densitometric evaluation of BAX mRNA induction after irradiation was determined as indicated in Fig. 2B and labeled as fold induction below the autoradiographs. (B) Densitometric evaluation of BAX mRNA induction after irradiation was determined for DAOY, SNB40, mp53.1, and vec.1 as indicated in Fig. 2B and expressed as fold induction on the bar graph. Each bar represents the mean ± SD of the results of three independent experiments.