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Effect of WAY100635 in the open field. (a) Mean path length ± SEM during 1 hr. There was no significant effect of genotype or treatment. (b) Mean time spent in the center of the open field (± SEM). There was a main effect of treatment [F(2,68) = 4.110; P < 0.05], a main effect of genotype [F(1,68) = 4.248; P < 0.05], and a treatment by genotype interaction [F(2,68) = 4.101; P < 0.05]. n = 12–14 mice per group. Fisher post-hoc comparisons: ∗, P < 0.05.
