Figure 1.

Reverse transcription-polymerase chain reaction analysis of the FP receptor gene in human ciliary bodies. (a) The location of PCR products of the correct size for known wild-type FP receptor, abbreviated as WT-FP, and FP receptor variants, abbreviated as AltFP, are indicated by arrows. Sequencing analysis showed that the band of altFP contains multiple FP receptor variants. (b) The black bars represent the coding sequence for the wild-type FP receptor. There are five additional exons generated by mRNA alternative splicing, located between exon 2 and exon 3 and indicated as exon A, exon B, exon C, exon D and exon E.