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. 2008 Jul;3(4):1102–1114. doi: 10.2215/CJN.04401007

Table 3.

Quality of systematic reviews

Parameter No. of Systematic Reviews OQAQ Score of Methodologic Quality (9 Points)
Overall Quality Score as per OQAQ Question 10 (Scale 1 to 7)
OQAQ Methodologic Errors
Mean (SD) P Mean (SD) P Major (n [%])a Minor (n [%])a P
All systematic reviews 90 6.0 (2.9) 3.4 (2.2) 49 (54) 41 (46)
Systematic reviews published in
    Journals 72 5.3 (2.8) <0.001 2.8 (1.9) <0.001 49 (68) 23 (32) <0.001
    Cochrane Reviews 18 8.8 (0.6) 5.9 (0.8) 0 (0) 18 (100)
Systematic reviews published in
    journals that require adherence to consensus guidelines for reporting of systematic reviews 11 8.0 (1.7) <0.001 4.7 (1.6) <0.001 2 (18) 9 (82) <0.001
    journals that do not require adherence to consensus guidelines for reporting of systematic reviews 61 4.8 (2.7) 2.4 (1.7) 47 (77) 14 (23)
Systematic reviews published in
    journals that require adherence to consensus guidelines for reporting of systematic reviews 11 8.0 (1.7) 0.650 4.7 (1.6) 0.140 2 (18) 9 (82) 0.420
    Cochrane reviews 18 8.8 (0.6) 5.9 (0.8) 0 (0) 18 (100)
Systematic reviews published in
    nephrology or transplant journals 25 6.2 (2.8) 0.090 3.3 (2.0) 0.140 14 (56) 11 (44) 0.180
    non-nephrology, non-transplant journals 47 4.9 (2.7) 2.5 (1.8) 35 (74) 12 (26)
Language restrictions
    no 32 8.4 (1.1) <0.001 5.5 (1.3) <0.001 4 (13) 28 (87) <0.001
    yes 24 5.6 (2.4) 2.6 (1.7) 17 (71) 7 (29)
    not reported 34 4.0 (2.6) 1.9 (1.4) 28 (82) 6 (18)
Primary study authors contacted
    yes 41 7.8 (1.9) <0.001 4.8 (1.8) <0.001 10 (24) 31 (76) <0.001
    no 49 4.5 (2.7) 2.1 (1.7) 39 (80) 10 (20)
Funding
    reported 52 7.3 (2.4) <0.001 4.3 (1.9) <0.001 18 (35) 34 (65) <0.001
    not reported 38 4.3 (2.6) 2.1 (1.8) 31 (82) 7 (18)
Impact factorb
    0.00 to 2.99 29 4.0 (2.4) <0.001 1.8 (1.2) <0.001 26 (90) 3 (10) <0.001
    ≥3.00 35 6.5 (2.5) 3.6 (2.0) 17 (49) 18 (51)
a

Studies were deemed to contain major methodological errors if the overall OQAQ score was less than or equal to 3. Studies were deemed to contain minor methodological errors if the overall OQAQ score was greater than or equal to 4.

b

Institute for Scientific Information impact factor was not available for 26 systematic reviews as ISI does not calculate an impact factor for the Cochrane database and nine journals (Chinese Journal of Evidence-Based Medicine, Clinical & Developmental Immunology, Core Evidence, Edtna-Erca Journal, Health Technology Assessment, Hemodialysis International and Minerva Uroloica E Nefrologica).