Table 6.

Adverse events experienced by more than one patient (safety population)

Adverse event(n [%])	50 IU/kg Three Times Weekly for 4 wk(n = 10)	10,000 IU Weekly for 4 wk(n = 9)	20,000 IU Every 2 wk for 4 wk(n = 9)	40,000 IU Every 4 wk for 8 wk(n = 10)	All(n = 38)
Peripheral edema	1 (10)	2 (22)	1 (11)	1 (10)	5 (13)
Gout	0 (0)	0 (0)	0 (0)	2 (20)	2 (5)
Back pain	0 (0)	1 (11)	1 (11)	0 (0)	2 (5)
Rheumatoid arthritis	0 (0)	1 (11)	0 (0)	1 (10)	2 (5)
Headache	0 (0)	0 (0)	0 (0)	2 (20)	2 (5)
Hypertension	1 (10)	0 (0)	0 (0)	1 (10)	2 (5)