Table 1.
Physiologic characteristics of ratsa
Characteristic | Control | CRF |
---|---|---|
Rats (n) | 38 | 39 |
Final body weight (g) | 345.00 ± 6.00 | 303.00 ± 9.00 |
Serum chemistry | ||
creatinine (μmol/L) | 55.00 ± 1.00 | 230.00 ± 13.00b |
urea (mmol/L) | 5.00 ± 0.20 | 50.00 ± 5.00b |
calcium (mmol/L)c | 1.39 ± 0.03 | 1.28 ± 0.08 |
phosphate (mmol/L) | 3.36 ± 0.10 | 3.78 ± 0.27 |
Creatinine clearance (μl/100 g per min) | 337.00 ± 14.00 | 69.00 ± 7.00b |
Data are means ± SEM.
P < 0.01 versus control group.
Ionized calcium concentration corrected at pH 7.4.